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Related Experiment Video

Updated: Jul 14, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
07:16

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

Ablation for paediatric solid tumours: current evidence from a scoping review.

Manal Dhaiban1, Nigel J Hall2

  • 1Cambridge University Hospital (CUH), 31 Pakenham Close, CB4 1PW, Cambridge, UK. manaldhaiban1985@gmail.com.

Pediatric Surgery International
|July 12, 2026
PubMed
Summary

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Ablation therapy is a safe and feasible option for treating paediatric solid tumours. However, inconsistent reporting limits current evidence, necessitating standardized multicentre studies for better outcomes.

Area of Science:

  • Oncology
  • Minimally Invasive Surgery
  • Paediatric Medicine

Background:

  • Ablation therapy presents a minimally invasive approach for select paediatric solid tumours.
  • Published outcomes for ablation in children are inconsistently reported, hindering evidence-based practice.

Purpose of the Study:

  • To conduct a scoping review of literature on ablation therapy for paediatric solid tumours.
  • To identify tumour types, anatomical sites, modalities, and reported outcomes of ablation in children.
  • To assess the safety and efficacy of ablation in paediatric solid tumour treatment.

Main Methods:

  • Scoping review of literature from 2000 to 2024.
  • Inclusion of studies reporting ablation in patients under 18 years with solid tumours.
Keywords:
CryoablationMicrowave ablationPaediatric solid tumoursRadiofrequency ablationScoping reviewThermal ablation

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Last Updated: Jul 14, 2026

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  • Extraction of data on tumour characteristics, ablation techniques, and oncological outcomes.

    • Main Results:

    • Thirty-three studies analyzed 202 children with 304 treated lesions.
    • Radiofrequency and microwave ablation were common modalities, with liver and lung being frequent sites.
    • Favourable local tumour control was reported, but definitions of response and recurrence varied significantly.
    • Major complications were infrequent, indicating general safety.

    Conclusions:

    • Ablation is technically feasible and generally safe for selected paediatric solid tumours.
    • Evidence is limited by small cohorts, retrospective designs, and heterogeneity in reporting.
    • Prospective, multicentre studies with standardized outcome definitions are crucial to refine indications and compare with surgical resection.