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Evaluation of the Intermittent Exotropia Questionnaire using Rasch analysis
David A Leske1, Jonathan M Holmes1, B Michele Melia2
1Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
JAMA Ophthalmology
|January 31, 2015
Summary
The Intermittent Exotropia Questionnaire (IXTQ) was refined using Rasch analysis to improve its accuracy in measuring quality of life for children with intermittent exotropia and their families.
Area of Science:
- Ophthalmology
- Pediatric Health
- Psychometrics
Background:
- Intermittent exotropia significantly impacts children's quality of life.
- Existing health-related quality of life measures require refinement for this population.
Purpose of the Study:
- To refine the Intermittent Exotropia Questionnaire (IXTQ) using Rasch analysis.
- To enhance the reliability and validity of the IXTQ for pediatric patients.
Main Methods:
- Rasch analysis applied to data from 575 children with intermittent exotropia and their parents.
- Item and response option modifications were made based on analysis.
- Validation in a separate cohort of 379 patients.
Main Results:
- One item removed from child and proxy questionnaires.
- Response options consolidated in older child and proxy questionnaires.
- Parent questionnaire yielded 3 subscales (psychosocial, function, surgery) after item removal.
Conclusions:
- The Rasch-revised IXTQ demonstrates potential as a reliable tool for assessing health-related quality of life in children with intermittent exotropia.
- This refined instrument is particularly valuable for cohort studies investigating the condition's impact.
