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Updated: Apr 18, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

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Complete Genome Sequence of Citrobacter freundii Myophage Moon

Garrett B Edwards1, Adrian J Luna1, Adriana C Hernandez1

  • 1Center for Phage Technology, Texas A&M University, College Station, Texas, USA.

Genome Announcements
|January 31, 2015
PubMed

Insights

A novel bacteriophage, Moon, targeting Citrobacter freundii was discovered. This T4-like myophage offers potential for controlling Gram-negative bacterial infections and aiding public health efforts.

Area of Science:

  • Microbiology
  • Genomics
  • Bacteriophage Therapy

Background:

  • Citrobacter freundii is a Gram-negative opportunistic pathogen of public health concern.
  • Bacteriophages (phages) are viruses that infect bacteria and can be used to combat bacterial infections.

Purpose of the Study:

  • To describe the genome of a newly isolated bacteriophage, named Moon.
  • To characterize Moon as a T4-like myophage targeting C. freundii.

Main Methods:

  • Isolation and characterization of a novel bacteriophage.
  • Whole-genome sequencing and analysis of the bacteriophage.

Main Results:

  • A new T4-like myophage, Moon, was successfully isolated.
  • The genome of bacteriophage Moon was sequenced and its features were analyzed.

Conclusions:

  • Bacteriophage Moon is a potential candidate for therapeutic applications against C. freundii infections.
  • Phage genomics provides insights into novel antimicrobial strategies.

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