Related Experiment Video

Updated: Apr 18, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

3.0K

Takotsubo cardiomyopathy secondary to intracranial hemorrhage

Mai Shimada1, Jonathan D Rose2

  • 1Maimonides Medical Center, New York 11219, NY, USA.

International Journal of Emergency Medicine
|January 31, 2015
PubMed

Insights

Aneurysmal subarachnoid hemorrhage can cause Takotsubo cardiomyopathy, mimicking heart attacks. Awareness of this link is crucial for timely diagnosis and treatment in patients with subarachnoid hemorrhage.

Area of Science:

  • Cardiology
  • Neurology
  • Critical Care Medicine

Background:

  • Aneurysmal subarachnoid hemorrhage (SAH) frequently causes electrocardiogram (ECG) abnormalities resembling cardiac ischemia.
  • Left ventricular regional wall-motion dysfunction is an infrequently reported complication of SAH.

Purpose of the Study:

  • To increase awareness of potential ECG changes associated with SAH.
  • To highlight the association between SAH and Takotsubo cardiomyopathy (TCM).

Main Methods:

  • Case report of a 55-year-old female patient with acute aneurysmal subarachnoid hemorrhage.
  • Evaluation complicated by the development of Takotsubo cardiomyopathy.

Main Results:

  • The patient's aneurysmal subarachnoid hemorrhage was complicated by Takotsubo cardiomyopathy.
  • Takotsubo cardiomyopathy presented similarly to acute ST-elevation myocardial infarction.

Conclusions:

  • Aneurysmal subarachnoid hemorrhage can induce Takotsubo cardiomyopathy.
  • Physicians must recognize this association to avoid diagnostic delays and ensure appropriate patient management.

Keywords:
Apical ballooning syndromeCardiomyopathyECG abnormalitiesIntracranial hemorrhageSubarachnoid hemorrhageTakotsubo

More Related Videos

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.7K
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

11.8K

Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
3
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
1
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
2
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
1
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
559