Spine fusion cross-link causing delayed dural erosion and CSF leak: case report
Gazanfar Rahmathulla1, H Gordon Deen
1Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida.
Journal of Neurosurgery. Spine
|January 31, 2015
Summary
Spinal fusion cross-links can cause rare complications like dural defects and CSF leaks years after surgery. Surgeons must ensure cross-links do not compress the dura to prevent these issues.
Area of Science:
- Neurosurgery
- Spinal Surgery
- Orthopedic Surgery
Background:
- Lumbar spinal fusion surgery has increased significantly over the past two decades.
- Cross-links are used in pedicle screw-rod constructs to enhance spinal stabilization and resistance to stress.
- These devices aim to improve fusion outcomes and construct rigidity.
Observation:
- A 49-year-old woman presented 11 years after L4-5 spinal fusion with a pedicle screw-rod construct including a cross-link.
- She developed severe symptoms including postural headaches, neurogenic claudication, and radiculopathy.
- Imaging showed spinal canal compression and a possible thickened filum terminale at the instrumented level.
Findings:
- Reexploration revealed a large erosive dural defect with a cerebrospinal fluid (CSF) leak.
- The cross-link was associated with spinal canal compression and a thickened filum terminale.
- This represents a rare, previously unreported complication of spinal fusion with cross-links.
Implications:
- This case highlights a rare complication associated with the use of cross-links in spinal fusion.
- It underscores the critical need to avoid dural compression when implanting spinal fusion hardware.
- Surgeons should be vigilant for delayed complications related to spinal instrumentation, even years post-surgery.
Related Concept Videos
Secondary Spinal Cord Injury llI: Pathophysiology
2
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
2
Cerebral Edema ll: Pathophysiology
1
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
1


