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The deep ocean and its underlying sediments represent vast, largely unexplored microbial habitats that extend far beyond the sunlit photic zone. The photic (euphotic) zone typically spans the upper ~100–200 meters of pelagic waters in the open ocean, but its depth varies geographically and seasonally, where sufficient light supports photosynthetic life. Below this lies the deep sea, spanning roughly 1000–6000 meters (bathypelagic to abyssal zones), with deeper hadal trenches...
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Quantitative Locomotion Study of Freely Swimming Micro-organisms Using Laser Diffraction
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2013 Lush Science Prize.

Rob Harrison1

  • 1Lush Prize Team, London, UK.

Alternatives to Laboratory Animals : ATLA
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Summary
This summary is machine-generated.

The Lush Science Prize recognizes 21st-century toxicology research, focusing on replacement alternatives and toxicity pathways. It highlights key projects and collaborative systems, recommending top papers for the 2013 award.

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Area of Science:

  • Toxicology Research
  • 21st Century Science
  • Environmental Health

Background:

  • Annual Lush Science Prize overview.
  • Focus on replacement alternatives in toxicology.
  • Exploration of toxicity pathways.

Purpose of the Study:

  • Provide judges with an overview of current developments.
  • Highlight key institutional projects like OECD's Adverse Outcome Pathway Project, Hamner Institute, and Human Toxome Project.
  • Discuss collaborative computer systems in toxicology.

Main Methods:

  • Literature review for background research.
  • Identification of key institutional developments.
  • Evaluation of collaborative computer systems.

Main Results:

  • Two highly-scored papers recommended for the 2013 Science Prize.
  • Overview of progress in replacement alternatives and toxicity pathways.
  • Summary of relevant institutional and technological advancements.

Conclusions:

  • The background paper serves as a crucial resource for the Lush Science Prize judging.
  • Progress in alternative methods and pathway elucidation is significant.
  • Collaborative systems are increasingly important in toxicological research.