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Non-cystic fibrosis bronchiectasis in children: clinical profile, etiology and outcome

Ajay Kumar1, Rakesh Lodha, Prawin Kumar

  • 1Departments of Pediatrics, Vardhaman Mahavir Medical College and Safdarjang Hospital, New Delhi; and *All India Institute of Medical Sciences, New Delhi, India. Correspondence to: Dr SK Kabra, Professor, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. skkabra@hotmail.com.

Indian Pediatrics
|February 2, 2015
PubMed

Insights

Non-cystic fibrosis bronchiectasis in children is often caused by infections or primary ciliary dyskinesia. Early diagnosis is crucial, as many children experience complications, require surgery, or sadly, pass away.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Research

Background:

  • Non-cystic fibrosis bronchiectasis is a chronic lung condition in children.
  • Understanding its causes and outcomes is vital for effective management.
  • Delayed diagnosis can lead to significant morbidity.

Purpose of the Study:

  • To detail the clinical characteristics, etiological factors, and outcomes.
  • To analyze the profile of pediatric patients with non-cystic fibrosis bronchiectasis.
  • To highlight the importance of timely diagnosis and intervention.

Main Methods:

  • Retrospective chart review of 80 children diagnosed with non-cystic fibrosis bronchiectasis.
  • Data collected from a pediatric chest clinic at a tertiary care hospital.
  • Analysis of clinical presentation, identified causes, and patient outcomes.

Main Results:

  • Etiology identified in 63.8% of cases; common causes include post-infectious (23.8%) and primary ciliary dyskinesia (15%).
  • Complications occurred in 95% of patients.
  • Surgery was needed for 17.5%, and mortality was 11.1%.

Conclusions:

  • Post-infectious causes and primary ciliary dyskinesia are frequent in pediatric non-cystic fibrosis bronchiectasis.
  • Increased awareness is needed for earlier diagnosis to improve outcomes.
  • Delayed diagnosis is a significant issue impacting patient prognosis.
Abstract

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