Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tilting towards a diagnosis in recurrent unexplained syncope.

A Fitzpatrick1, R Sutton

  • 1Cardiac Department, Westminster Hospital, London.

Lancet (London, England)
|March 25, 1989
PubMed
Summary

Head-up tilt testing effectively diagnosed vasovagal syncope in 74% of patients with unexplained recurrent syncope. Dual-chamber pacing can prevent syncope and improve hemodynamic function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical challenges and proposed solutions for patients with invasive lobular breast cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2025
Same author

A framework for clinical care pathway renewal: an example from inflammatory bowel disease.

BMC medical research methodology·2025
Same author

Feasibility and acceptability of a culinary nutrition programme for adults with mild-to-moderate intellectual disability: FLIP Food and Lifestyle Information Programme.

Journal of applied research in intellectual disabilities : JARID·2024
Same author

Anaesthetic subspecialties and sustainable healthcare: a narrative review.

Anaesthesia·2024
Same author

The KMT2A recombinome of acute leukemias in 2023.

Leukemia·2023
Same author

Syncope presenting to the emergency department.

Journal of internal medicine·2021

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Physiology

Background:

  • Recurrent syncope often remains unexplained after initial investigations.
  • Vasovagal syncope is a common cause of syncope, but diagnosis can be challenging.

Purpose of the Study:

  • To evaluate the diagnostic utility of 60-degree head-up tilt testing in patients with unexplained recurrent syncope.
  • To assess the efficacy of dual-chamber pacing in managing syncope induced by head-up tilt.

Main Methods:

  • 71 patients with unexplained recurrent syncope underwent 60-degree head-up tilt testing.
  • Symptoms, heart rate, and blood pressure were monitored during the tilt procedure.
  • Temporary dual-chamber pacing was employed in a subset of patients.

Main Results:

  • Head-up tilt reproduced syncope in 53 patients (74%), primarily vasovagal syncope with bradycardia or vasodepression.
  • Syncope occurred at a mean of 25 minutes after tilting.
  • Temporary dual-chamber pacing aborted syncope in 85% of patients and improved hemodynamic parameters.

Conclusions:

  • Head-up tilt testing is a valuable tool for diagnosing unexplained recurrent syncope.
  • Dual-chamber pacing is an effective intervention for patients experiencing syncope during tilt testing, suggesting potential long-term benefits.

Related Experiment Videos