Clinical experience with cone-beam CT navigation for tumor ablation
Nadine Abi-Jaoudeh1, Aradhana M Venkatesan1, William Van der Sterren2
1Department of Radiology and Imaging Sciences, National Institutes of Health, Room 1C365 Building 10 MSC 1182, 9000 Rockville Pike, Bethesda, MD 20892.
Journal of Vascular and Interventional Radiology : JVIR
|February 4, 2015
Summary
Cone-beam CT navigation enhances percutaneous tumor ablation by improving guidance and monitoring. This image-guided technique demonstrated high technical success rates and effective tumor coverage in a clinical setting.
Area of Science:
- Medical Imaging
- Interventional Radiology
- Oncology
Background:
- Percutaneous tumor ablation is a minimally invasive treatment option for various cancers.
- Accurate guidance and real-time monitoring are crucial for successful ablation outcomes.
- Traditional imaging methods may have limitations in providing comprehensive intraprocedural information.
Purpose of the Study:
- To evaluate the clinical utility and benefits of cone-beam CT (CBCT) navigation for image-guided percutaneous tumor ablation.
- To assess the impact of CBCT navigation on ablation planning, execution, and verification.
Main Methods:
- Retrospective analysis of 20 percutaneous tumor ablations in 16 patients using CBCT navigation between February 2011 and February 2013.
- CBCT capabilities included multimodality image fusion, tumor segmentation, predicted ablation zone visualization, and post-ablation verification.
- Ablation plans were recorded, and technical success, effectiveness rates, and local recurrences were assessed.
Main Results:
- CBCT navigation facilitated image fusion and intraprocedural planning, with 14 of 20 ablations showing no deviation from the initial plan.
- An average of 8.7 CBCT scans per procedure were used for planning, probe positioning, and coverage verification.
- Technical success rate was 96.5% (28/29 lesions), with high technical effectiveness at 1 month (96.1%) and last follow-up (84.6%) for curative intent ablations. Local tumor progression was observed in 11.5% of lesions.
Conclusions:
- Cone-beam CT navigation provides valuable information that assists and enhances guidance and monitoring during percutaneous tumor ablation.
- The integration of CBCT navigation contributes to improved procedural accuracy and potentially better patient outcomes in tumor ablation.
