Related Experiment Video
Updated: Apr 17, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Improving pharmaceutical innovation by building a more comprehensive database on drug development and use
Gregory W Daniel1, Alexis Cazé2, Morgan H Romine3
1Gregory W. Daniel (GDaniel@brookings.edu) is a fellow and managing director for evidence development and innovation at the Engelberg Center for Health Care Reform at Brookings, in Washington, D.C.
Pharmaceutical innovation metrics are being developed to better assess drug development trends. This new framework aims to provide comprehensive, publicly available data on new molecular entities and their outcomes.
Area of Science:
- Pharmaceutical sciences
- Health economics
- Biotechnology
Background:
- Despite increased research and development spending, pharmaceutical innovation appears to be stagnating.
- Current measures of pharmaceutical innovation are limited in scope and accuracy.
Purpose of the Study:
- To address limitations in current pharmaceutical innovation metrics.
- To develop a comprehensive, publicly available framework for assessing drug innovation.
Main Methods:
- Reviewing existing literature on pharmaceutical innovation measurement.
- Collaborating with experts in drug development and regulatory review.
- Collecting data on new molecular entities approved in the US and EU over several decades.
Main Results:
- Identification of key development and regulatory characteristics for new molecular entities.
- Establishment of a collaborative framework for data collection and metric development.
Conclusions:
- A comprehensive database of drug innovation metrics is needed.
- Improved metrics will enable better analysis of innovation drivers, trends, and policy impacts.
More Related Videos
08:31Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
Published on: December 1, 2020
08:15Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
Published on: May 10, 2024
Related Concept Videos
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Discovery: Overview
Drug Regulation
Clinical Trials: Overview
Biopharmaceutical Factors Influencing Drug Product Design: Overview