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Updated: Apr 17, 2026

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
Published on: March 13, 2018
Radiopharmaceuticals as probes to characterize tumour tissue
Israt S Alam1, Mubarik A Arshad, Quang-Dé Nguyen
1Comprehensive Cancer Imaging Centre, Imperial College London, London, W12 0NN, UK.
Abstract:
Tumour cells exhibit several properties that allow them to grow and divide. A number of these properties are detectable by nuclear imaging methods. We discuss crucial tumour properties that can be described by current radioprobe technologies, further discuss areas of emerging radioprobe development, and finally articulate need areas that our field should aspire to develop. The review focuses largely on positron emission tomography and draws upon the seminal 'Hallmarks of Cancer' review article by Hanahan and Weinberg in 2011 placing into context the present and future roles of radiotracer imaging in characterizing tumours.
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