The potential use of cell-based therapies in the treatment of oral diseases
Related Experiment Video
Updated: Apr 17, 2026

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
Published on: April 13, 2022
H Kagami1,2,3
1Department of Oral and Maxillofacial Surgery, Matsumoto Dental University Dental School, Shiojiri.
Abstract:
A recent and exciting development in medicine is the use of living cells for patient treatment. The utility of living cells to treat diseases was first proved in hematopoietic stem cell transplantation for leukemia patients. This approach has been expanded for other diseases such as islet transplantation for diabetic patients. In those cases, the cells were isolated from donors or the patient and used without complex manipulation. Since the 1980s, cells have been expanded outside of the body for the treatment of burn patients' skin. This novel treatment strategy is designated 'tissue engineering' and has been successfully applied for treatment of skin, cartilage, and also bone defects. Due to the recent developments in stem cell science, this area has attracted much attention and the application has been expanding. In this review, the potential of cell-based therapy for oral diseases is discussed with a concise review of recent developments in this field.
More Related Videos
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
05:32In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells
Published on: February 16, 2024
Related Concept Videos
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Stem Cell Culture
Tumor Immunotherapy
iPS Cell Differentiation
Microorganisms in Medicine and Therapeutics
Mesenchymal Stem Cells