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Updated: Apr 17, 2026

Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
Published on: September 19, 2011
From PAWP to "Pop": opening up new pathways to fatherhood
Melissa L Vadnais, George L Gerton1
1Center for Research on Reproduction and Women's Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6160, USA.
Abstract:
Infertility remains a significant problem for many couples. Approximately one in seven couples who attempt to conceive will fail to do so within 1 year. In about 65% of these cases, there is a male component of infertility.1 Despite normal semen parameters, the etiology of infertility remains uncertain in more than 50% of couples.2 Defects in sperm proteins and/ or structures may underlie certain cases of male infertility. Although many men would like to be called "Pop", "Dad", or "Papa", those who are classified with idiopathic male infertility have few options for becoming fathers. Recent studies by Aarabi et al.3 may open the door to new therapies.
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