Related Experiment Video
Updated: Apr 17, 2026
06:59
Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
748
Thrombotic Complications during Interventional Lung Assist: Case Series
Eun Jung Kim1, Woo Hyun Cho1, Eun Young Ahn1
1Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
Tuberculosis and Respiratory Diseases
|February 6, 2015
Summary
Interventional lung assist (iLA) is effective for hypercapnia but carries risks. This study highlights two cases of thrombotic complications during iLA, emphasizing the need to monitor blood flow and anticoagulation to prevent these serious issues.
Area of Science:
- Critical care medicine
- Pulmonary medicine
- Vascular access
Background:
- Interventional lung assist (iLA) is a vital extracorporeal support system for managing life-threatening hypercapnia.
- Despite its efficacy in reducing CO2 and enabling protective ventilation, iLA is associated with significant complications including bleeding, thrombosis, and limb ischemia.
Purpose of the Study:
- To present two clinical cases of thrombotic complications occurring during iLA therapy.
- To elucidate the potential causes of these thrombotic events in the context of iLA.
Main Methods:
- Case report analysis of two patients undergoing iLA for hypercapnic respiratory failure.
- Review of clinical data, including blood flow parameters and anticoagulation regimens, in relation to thrombotic event occurrence.
Main Results:
- Thrombotic complications were observed in both presented cases during iLA treatment.
- Analysis suggested that stasis from low blood flow and insufficient anticoagulation were the primary contributing factors to thrombosis.
Conclusions:
- Thrombotic complications are a significant risk during iLA therapy.
- Close monitoring of blood flow dynamics and optimization of anticoagulation strategies are crucial for mitigating thrombotic risks associated with iLA.
Related Concept Videos
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
709
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
709
01:27Pulmonary Embolism III: Nursing Management
709
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
709
01:19Pulmonary Embolism I: Introduction
2
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
2
01:29Pulmonary Embolism I: Introduction
1.4K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.4K
01:29Venous Thrombosis III: Interprofessional Care
473
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
473
01:26Endoscopic Studies II: Thoracocentesis
2.3K
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
2.3K