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An Integrated Approach for Microprotein Identification and Sequence Analysis
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Viewing multiple sequence alignments with the JavaScript Sequence Alignment Viewer (JSAV).

Andrew C R Martin1

  • 1Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London, WC1E 6BT, UK.

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|February 6, 2015
PubMed
Summary
This summary is machine-generated.

The JavaScript Sequence Alignment Viewer (JSAV) is a web tool for displaying biological sequence alignments. It offers customizable features for sequence visualization and data submission, enhancing web-based bioinformatics.

Keywords:
JavaScriptproteinsequence alignment

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Web Development

Background:

  • Displaying biological sequence alignments on web pages is crucial for data sharing and analysis.
  • Existing tools may lack flexibility or browser compatibility.
  • There is a need for a simple, configurable JavaScript component for this purpose.

Purpose of the Study:

  • To develop a user-friendly JavaScript component for displaying sequence alignments.
  • To provide customizable features for sequence visualization.
  • To ensure broad browser compatibility.

Main Methods:

  • Implementation as a pure JavaScript component named JavaScript Sequence Alignment Viewer (JSAV).
  • Utilization of JQuery and JQuery-UI libraries.
  • Avoidance of HTML5-specific features for enhanced browser compatibility.

Main Results:

  • JSAV offers highly configurable sequence display options, including alternative coloring schemes and sorting.
  • Features like 'dotifying' repeated amino acids are included.
  • The component supports submitting selected sequences to external web sites or JavaScript code.

Conclusions:

  • JSAV provides a flexible and compatible solution for web-based sequence alignment visualization.
  • The tool is well-documented (JSDOC) and readily available for integration.
  • It simplifies the process of sharing and interacting with biological sequence data online.