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Balance dysfunction in Parkinson's disease.
Steno Rinalduzzi1, Carlo Trompetto2, Lucio Marinelli2
1Neurology and Neurophysiopathology, Sandro Pertini Hospital, Via Monti Tiburtini 385, 00157 Rome, Italy.
Biomed Research International
|February 6, 2015
Summary
Parkinson's disease (PD) disrupts automatic postural control, affecting balance and mobility. This review examines how PD impairs sensorimotor functions critical for stability and safe movement.
Area of Science:
- Neuroscience
- Motor Control
- Clinical Neurology
Background:
- Functional motor activities rely on automatic regulation of muscle activity.
- Postural control integrates multisensory information for motor adjustments.
- Parkinson's disease (PD) frequently impairs these sensorimotor systems.
Purpose of the Study:
- To review the multifaceted ways Parkinson's disease impacts posture and balance.
- To consolidate existing experimental evidence on PD-related postural deficits.
Main Methods:
- Literature review of experimental studies on Parkinson's disease and postural control.
- Analysis of sensorimotor integration and its disruption in PD.
Main Results:
- Postural instability is a primary disabling symptom in Parkinson's disease.
- PD causes multilevel impairments affecting balance control.
- Disrupted sensorimotor control contributes significantly to disability in PD patients.
Conclusions:
- Parkinson's disease profoundly affects the complex mechanisms of posture and balance.
- Impaired balance control in PD exacerbates physical and psychosocial disability.
- Understanding these impairments is crucial for managing PD symptoms.
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