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Seizing upon mechanisms for impaired consciousness
Zoya Farzampour1, John Huguenard1
1Stanford Neuroscience Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Neuron
|February 6, 2015
Abstract:
Transient loss of consciousness associated with focal temporal lobe seizures is a complex phenomenon with life-threatening repercussions. In this issue of Neuron, Motelow et al. (2015) describe decreased cholinergic drive and suppressed subcortical arousal in seizures as a novel mechanism for impaired cortical function.