Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

1.9K
Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
1.9K
Capillary Electrophoresis: Instrumentation01:20

Capillary Electrophoresis: Instrumentation

1.8K
Capillary electrophoresis instrumentation typically consists of several key components. A high-voltage power supply generates the electric field necessary for the separation by connecting to an anode (the positively charged electrode) and a cathode (the negatively charged electrode) located in buffer reservoirs at each end of the capillary tube. The system includes a sample vial, a fused silica capillary tube coated with polyimide for mechanical strength through which the sample components...
1.8K
Electrophoresis: Overview01:20

Electrophoresis: Overview

5.2K
Electrophoresis is a powerful analytical separation technique that relies on the differential migration of charged species when subjected to an electric field. The core strength of electrophoresis lies in its ability to separate high-molecular-weight species in complex mixtures. It has found widespread use in biochemistry, molecular biology, and analytical chemistry, allowing the separation of compounds like amino acids, nucleotides, carbohydrates, and proteins with excellent resolution.
There...
5.2K
Two-dimensional Gel Electrophoresis01:22

Two-dimensional Gel Electrophoresis

8.4K
Two-dimensional gel electrophoresis is a high-resolution protein separation method first introduced by O' Farrell and Klose in 1975. This method involves protein separation by two dimensions, mass and charge, making it more accurate than one-dimensional gel electrophoresis.
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such...
8.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microfluidic co-culture system for synaptically segregated neural networks to explore astrocyte-driven neural pathology.

Microsystems & nanoengineering·2026
Same author

Impact of Surface Biofouling on Controlled Drug Release from Conductive Polymer Films and Its Mitigation Using Lubricin (Proteoglycan 4) Antifouling Coatings.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

A Scalable Synthetic Approach for Producing Homogeneous, Large Area 2D Highly Conductive Polymers.

ACS applied materials & interfaces·2025
Same author

Method for lysis and paper-based elution-free DNA extraction with colourimetric isothermal amplification.

Scientific reports·2024
Same author

3D printed porous membrane integrated devices to study the chemoattractant induced behavioural response of aquatic organisms.

Lab on a chip·2024
Same author

Chemical Trends in Sample Preparation for Nucleic Acid Amplification Testing (NAAT): A Review.

Biosensors·2023
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

Related Experiment Video

Updated: Apr 17, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.1K

Versatile electrophoresis-based self-test platform.

Rosanne M Guijt1

  • 1Australian Centre for Research on Separation Science (ACROSS), School of Medicine, University of Tasmania, Australia; KIST-Europe, Saarbrücken, Germany.

Electrophoresis
|February 7, 2015
PubMed
Summary
This summary is machine-generated.

Lab on a Chip (LOC) devices enable automated chemical analysis outside the lab. This research details electrophoresis-based LOC for self-testing ionic analytes, enhancing diagnostic accuracy and reliability.

More Related Videos

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.6K
Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

10.5K

Related Experiment Videos

Last Updated: Apr 17, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.1K
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.6K
Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

10.5K

Area of Science:

  • Analytical Chemistry
  • Biomedical Engineering
  • Point-of-Care Diagnostics

Background:

  • Lab on a Chip (LOC) technology facilitates automated, on-site chemical analysis.
  • Point-of-care (POC) devices are crucial for rapid diagnostics in healthcare.
  • Electrophoresis-based LOC offers a portable solution for analyzing ionic analytes.

Purpose of the Study:

  • To describe the research behind electrophoresis-based POC devices for self-testing ionic analytes.
  • To detail hardware, software, and methodological improvements for enhanced analytical performance.
  • To explore new applications beyond lithium monitoring, including veterinary uses and other analytes.

Main Methods:

  • Development of electrophoresis-based Lab on a Chip devices.
  • Optimization of hardware and software for improved analytical performance.
  • Methodological advancements for accuracy, precision, and reliability.

Main Results:

  • Demonstrated improved accuracy, precision, detection limits, and reliability of the LOC devices.
  • Successfully applied the platform for lithium monitoring.
  • Expanded applications to veterinary diagnostics, sodium, and creatinine measurements.

Conclusions:

  • Electrophoresis-based LOC technology provides a robust platform for self-testing ionic analytes.
  • The developed devices offer enhanced analytical performance for various diagnostic applications.
  • The platform shows significant potential for point-of-care testing in healthcare and veterinary medicine.