Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

2.0K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
2.0K
Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

1.0K
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel approach to radioembolization treatment planning using a hybrid [<sup>99m</sup>Tc]Tc-MAA contrast enhanced SPECT/CT.

European journal of nuclear medicine and molecular imaging·2026
Same author

Radioembolization Practice in North America Versus Europe: Results from a Global Survey.

Current oncology (Toronto, Ont.)·2026
Same author

Correcting fast irregular motion in PET: maximum-likelihood motion and activity (MLMA) reconstruction.

EJNMMI physics·2026
Same author

A Federated Benchmark for Clinical Natural Language Processing (FedDRAGON).

Studies in health technology and informatics·2026
Same author

Motion mitigation in positron-emission tomography guided radiotherapy delivered on a magnetic resonance imaging-linear accelerator.

Physics and imaging in radiation oncology·2026
Same author

Reference tissue uptake of [18F]PSMA-1007 in positron emission tomography of recurrent prostate cancer.

European radiology·2026

Related Experiment Video

Updated: Apr 17, 2026

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

12.9K

A parallel-cone collimator for high-energy SPECT.

Casper Beijst1, Mattijs Elschot2, Max A Viergever3

  • 1Radiology and Nuclear Medicine, UMC Utrecht, Utrecht, The Netherlands; and Image Sciences Institute, UMC Utrecht, Utrecht, The Netherlands cbeijst@umcutrecht.nl.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|February 7, 2015
PubMed
Summary

A novel parallel-cone (PC) collimator improves high-energy SPECT imaging quality by reducing septal penetration. This advanced collimator design enhances image resolution and contrast recovery for isotopes like Iodine-131.

Keywords:
SPECTcollimatorhigh-energy SPECTparallel cone collimator

More Related Videos

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

3.0K
Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis
07:24

Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis

Published on: May 10, 2021

7.0K

Related Experiment Videos

Last Updated: Apr 17, 2026

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

12.9K
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

3.0K
Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis
07:24

Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis

Published on: May 10, 2021

7.0K

Area of Science:

  • Nuclear Medicine
  • Medical Imaging Physics
  • Radiological Sciences

Background:

  • High-energy Single Photon Emission Computed Tomography (SPECT) imaging often uses parallel-hole collimators with thick septa to mitigate septal penetration.
  • This mitigation, however, comes at the expense of reduced sensitivity and image resolution.
  • Alternative collimator designs are needed to overcome these limitations.

Purpose of the Study:

  • To investigate a novel parallel-hole collimator with cone-shaped holes, termed the parallel-cone (PC) collimator.
  • To assess the potential of a single-slice prototype PC collimator to enhance image quality in high-energy SPECT imaging.
  • To compare the performance of the PC collimator against standard clinical collimators.

Main Methods:

  • Quantitative comparison of image quality using Monte Carlo simulations and experimental phantom studies.
  • Assessment of sensitivity and resolution through point-spread function (PSF) analysis of single and double point sources.
  • Evaluation of contrast recovery coefficients and image noise at equal noise levels.

Main Results:

  • Monte Carlo simulations demonstrated reduced PSF broadening due to collimator penetration for the PC collimator compared to the high-energy general-purpose (HEGP) collimator.
  • The PC collimator enabled separate detection of point sources that were not resolvable with the HEGP collimator at clinically relevant distances.
  • Phantom studies showed significantly improved contrast recovery coefficients for the PC collimator with high-energy isotopes (Iodine-131, Fluorine-18) compared to the HEGP collimator.

Conclusions:

  • A single-slice prototype of the parallel-cone (PC) collimator shows significant potential for improving image quality in high-energy SPECT imaging.
  • The PC collimator design offers a promising alternative to standard parallel-hole collimators for specific clinical applications.
  • Further development and validation of the PC collimator could lead to enhanced diagnostic capabilities in nuclear medicine.