Related Experiment Video
Updated: Apr 17, 2026
An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
[Pericardial effusion predicts mortality in patients with chronic obstructive pulmonary disease]
Can Yücel Karabay1, Gökhan Göl2, Arzu Kalaycı3
1Department of Cardiology, Süreyyapaşa Thoracic Surgery Training and Research Hospital, İstanbul, Turkey. karabaymd@yahoo.com.
Objectives:
Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity and mortality worldwide. Pericardial effusion (PE) is a current issue proven to be a mortality predictor, especially in pulmonary arterial hypertension. In this study, we aimed to evaluate the prognostic value of PE in COPD.
Study Design:
The study cohort consisted of 488 COPD patients and a control group of 50 healthy patients. At the start of the study, 37 patients (7.5%) had PE. Mean follow-up time was 12 months (range; 1-16 months). Clinical spirometric and echocardiographic data were compared between patients with PE(+) group (n=37), patients without PE(-) group (n=451) and the healthy control group.
Results:
Right ventricular functions were more depressed and pulmonary arterial pressure was more elevated in the PE(+) group. Also, Kaplan-Meier survival curve analysis showed that at one-year follow- up, mortality was higher in the PE(+) group: PE(-) group 139 (30.8%), PE(+) group 21 (56.8%) log-Rank p value: 0.009). Age, presence of PE, and oxygen usage were independent predictors of mortality in Cox regression analysis.
Conclusion:
Presence of PE predicts mortality in COPD patients at one-year follow-up.
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