Related Experiment Video

Updated: Apr 17, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
12:15

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

Published on: February 8, 2022

3.1K

The morphologic and functional features of LAD myocardial bridging at multi-detector computed tomography coronary

Alper Aydın1, Rahmi Çubuk2, Mehmet Mahir Atasoy2

  • 1Department of Cardiology, Bahçeşehir University Faculty of Medicine, İstanbul, Turkey. dralperaydin@gmail.com.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|February 7, 2015
PubMed

Insights

Myocardial bridging (MB) depth, evaluated by MDCT coronary angiography, correlates with systolic compression. However, MB morphologic features do not predict coronary artery disease (CAD) presence.

Area of Science:

  • Cardiovascular Imaging
  • Cardiac Anatomy
  • Interventional Cardiology

Background:

  • Myocardial bridging (MB) is a congenital anomaly where a segment of a coronary artery tunneled within the myocardium.
  • The clinical significance of MB and its association with atherosclerosis remain areas of active investigation.

Purpose of the Study:

  • To retrospectively assess morphologic and functional characteristics of MB using multi-detector computed tomography (MDCT) coronary angiography.
  • To investigate the relationship between MB morphologic features and the presence of atherosclerosis in the coronary arteries.

Main Methods:

  • Retrospective analysis of 191 consecutive patients undergoing MDCT coronary angiography.
  • Detailed evaluation of MB morphologic features, including depth, length, and distance from the left coronary ostium.
  • Correlation analysis between MB characteristics, systolic compression, and coronary artery disease (CAD) presence.

Main Results:

  • MB was detected in 41 patients (21.5%), predominantly in the left anterior descending artery.
  • A significant correlation was observed between the percentage of systolic compression and the depth of the tunneled MB segment (r=0.538, p<0.01).
  • No significant relationship was found between MB morphologic features (depth, length, distance from ostium) and the presence of proximal CAD.

Conclusions:

  • MDCT coronary angiography effectively visualizes MB morphologic and functional attributes.
  • MB depth is a key determinant of systolic compression, while other morphologic features do not appear to influence compression or predict CAD.
  • Further research is warranted to elucidate the precise role of MB in the pathogenesis of coronary atherosclerosis.
Abstract

More Related Videos

3D Whole-heart Myocardial Tissue Analysis06:53

3D Whole-heart Myocardial Tissue Analysis

Published on: April 12, 2017

9.5K
Author Spotlight: Enhancing Coronary Artery Revascularization05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

1.4K

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
631
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
504
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.0K
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
482