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Constrictive pericarditis in a contemporary Danish cohort: aetiology and outcome

Nadia Lander Landex1, Nikolaj Ihlemann, Peter Skov Olsen

  • 1Department of Cardiology and Cardiothoracic Surgery , Rigshospitalet, Copenhagen , Denmark.

Scandinavian Cardiovascular Journal : SCJ
|February 7, 2015
PubMed

Insights

Constrictive pericarditis diagnosis and outcomes were studied in Danish patients. Pericardiectomy improved symptoms in most patients, with some echocardiographic markers normalizing post-surgery.

Area of Science:

  • Cardiology
  • Cardiac Surgery

Background:

  • Constrictive pericarditis aetiology and outcomes vary geographically and over time.
  • Contemporary data on diagnosis and outcomes in Danish patients are limited.

Purpose of the Study:

  • To describe the diagnostic work-up for constrictive pericarditis.
  • To evaluate the outcomes of patients with constrictive pericarditis in a contemporary Danish cohort.

Main Methods:

  • Retrospective analysis of hospital databases for patients diagnosed with constrictive pericarditis (1998-2012).
  • Inclusion criteria: cardiac catheterisation for suspected constrictive pericarditis, pericardiectomy, or discharge diagnosis of constrictive pericarditis.
  • Diagnostic methods included echocardiography and cardiac catheterisation.

Main Results:

  • 57 patients identified with constrictive pericarditis.
  • Previous surgery and inflammatory disease were common causes.
  • Echocardiography revealed dilated inferior caval vein, increased E/A ratio, high septal tissue velocity, and septal bounce.
  • 47 patients underwent pericardiectomy with 8.5% 30-day mortality.
  • 69% of patients showed clinical improvement; echocardiographic parameters normalized over time.

Conclusions:

  • Long-term outcome after pericardiectomy is acceptable.
  • Clinical improvement and partial resolution of echocardiographic findings are common post-pericardiectomy.
Abstract

Keywords:
constrictionpericardial diseasepericardiectomypericarditis

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