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Successful treatment of dysgeusia after middle-ear surgery with amitriptyline: Case report
Vyacheslav Makler1, N Scott Litofsky1
1Division of Neurological Surgery, University of Missouri School of Medicine, Columbia, MO.
Introduction:
The chorda tympani branches off of the facial nerve within the petrous portion of the temporal bone, and is responsible for controlling the taste in the anterior two-thirds of the tongue on each side. Due to its location, it is commonly injured during middle-ear surgery resulting in dysgeusia.
Method:
A case of a 59-year-old male had recurrent otitis media resulting in tympanic membrane perforation. Patient subsequently underwent lateral graft tympanoplasty. Shortly after surgery patient reported onset of dysgeusia consisting of metallic taste at the tip of the tongue and salty taste on the left side of the tongue.
Results:
Treatment with Amitriptyline 50mg each night significantly improved the patient's symptoms of dysgeusia.
Conclusions:
Amitriptyline may be an effective treatment for dysgeusia occurring after middle-ear surgery.

