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Silver nanoparticles in dental biomaterials.
Juliana Mattos Corrêa1, Matsuyoshi Mori2, Heloísa Lajas Sanches3
1Department of Operative Dentistry, Fluminense Federal University, 28625-650 Nova Friburgo, RJ, Brazil.
International Journal of Biomaterials
|February 11, 2015
Summary
Silver nanoparticles offer potent antimicrobial effects in dentistry, reducing biofilm formation on dental materials. Further research is needed to optimize silver nanoparticle concentration and release for long-term effectiveness.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Dental Materials
Background:
- Silver's historical use for antimicrobial properties.
- Synthesis and incorporation of silver nanoparticles (AgNPs) into biomaterials.
- AgNPs' effectiveness at low concentrations due to their small size.
Purpose of the Study:
- Review current progress of AgNPs in dentistry.
- Highlight AgNPs' antimicrobial potential, mechanical properties, cytotoxicity, and long-term effectiveness.
- Identify research gaps regarding optimal AgNP concentration and release.
Main Methods:
- Literature review of studies on AgNPs in dental biomaterials.
- Analysis of AgNP incorporation methods.
- Evaluation of reported antimicrobial efficacy, mechanical performance, and cytotoxicity data.
Main Results:
- AgNPs demonstrate significant antimicrobial potential against biofilm formation on dental surfaces.
- Incorporation of AgNPs can influence the mechanical properties of dental biomaterials.
- Cytotoxicity data requires careful consideration for clinical application.
Conclusions:
- AgNPs show promise for preventing biofilm in dentistry.
- Further studies are essential to determine optimal AgNP dosage and controlled release.
- Balancing antimicrobial efficacy with material integrity and safety is crucial.
