Related Experiment Video
Updated: Apr 17, 2026

07:34
Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
Published on: November 17, 2023
1.4K
Do emergency department patients receive a pathological diagnosis? A nationally-representative sample
Leana S Wen1, Janice A Espinola2, Joshua M Kosowsky3
1George Washington University, Department of Emergency Medicine, Washington, District of Columbia.
The Western Journal of Emergency Medicine
|February 12, 2015
Summary
Many emergency department (ED) patients, particularly those with chest, abdominal, or headache pain, do not receive a pathological diagnosis. This study found the rate of pathological diagnoses decreased from 1993 to 2009.
Area of Science:
- Emergency Medicine
- Diagnostic Accuracy
- Health Services Research
Background:
- Pathological diagnoses are crucial for understanding patient symptoms and guiding treatment.
- Previous studies suggest a significant number of emergency department (ED) patients are discharged without a definitive pathological diagnosis.
- This study investigates trends in pathological diagnoses at ED discharge using national data.
Purpose of the Study:
- To determine the proportion of patients discharged from the ED with a pathological diagnosis for common chief complaints (chest pain, abdominal pain, headache).
- To analyze trends in the rate of pathological discharge diagnoses from 1993 to 2009.
- To identify patient and visit characteristics associated with receiving a pathological diagnosis.
Main Methods:
- Analysis of 17 years (1993-2009) of data from the National Hospital Ambulatory Medical Care Survey (NHAMCS).
- Inclusion of adult patients (≥18 years) discharged from the ED with chief complaints of chest pain, abdominal pain, or headache.
- Categorization of discharge diagnoses as symptomatic or pathological, with trend analysis using logistic regression.
Main Results:
- An estimated 164 million adult ED visits for the studied complaints resulted in discharge home.
- Proportions of pathological discharge diagnoses were 55% (chest pain), 71% (abdominal pain), and 70% (headache).
- The overall proportion of pathological discharge diagnoses decreased from 72% to 63% between 1993 and 2009.
Conclusions:
- A substantial number of patients are discharged from the ED without a pathological diagnosis explaining their symptoms.
- Despite advancements in diagnostics, the rate of pathological discharge diagnoses has declined.
- Further research is needed to understand the reasons for this trend and its impact on clinical outcomes.

