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Left ventricular thrombus in patients with acute anterior wall myocardial infarction
Insights
Left ventricular thrombus (LVT) affects 34.1% of patients with acute anterior myocardial infarction (MI). Early hospitalization and ST-elevation MI (STEMI) are key factors influencing LVT risk.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Left ventricular thrombus (LVT) is a significant complication of acute myocardial infarction (MI).
- LVT increases the risk of systemic embolization.
- The frequency of LVT in acute anterior wall MI requires further investigation.
Purpose of the Study:
- To determine the frequency of left ventricular thrombus (LVT) in patients experiencing acute anterior wall myocardial infarction (MI).
Main Methods:
- A descriptive cross-sectional study was conducted at Ayub Teaching Hospital, Abbottabad.
- Data was collected from 85 patients diagnosed with acute anterior MI between April and October 2011.
- Echocardiography was used to diagnose LVT, and data were analyzed using SPSS-16.
Main Results:
- The study included 85 patients with acute anterior MI (68.2% males, 31.8% females).
- Left ventricular thrombus (LVT) was detected in 34.1% of patients via echocardiography.
- ST-elevation MI (STEMI) patients had a higher incidence of LVT (43.1%) compared to non-ST-elevation MI (NSTEMI) patients (5%). Patients diagnosed more than 12 hours after symptom onset had a significantly higher LVT rate (63.6%).
Conclusions:
- The incidence of LVT following acute anterior MI in the studied population is substantial.
- Risk factors for LVT include male gender, age over 50, and STEMI.
- Prompt hospitalization appears to reduce the risk of developing LVT.
Background:
Left ventricular thrombus (LVT) is a frequent and potentially dangerous complication of acute myocardial infarction and is associated with increased risk of systemic embolization. This study was conducted to determine the frequency of left ventricular thrombus in patients with acute anterior wall myocardial infarction.
Methods:
This descriptive cross-sectional study was conducted in departments of Medicine and Cardiology, Ayub Teaching Hospital, Abbottabad, from 15th April to 15th October, 2011. Patients diagnosed with acute anterior myocardial infarction (MI) of all ages and either gender were included in the study on the basis on non-probability consecutive sampling. The data was collected through a structured pro forma and analysed using SPSS-16.
Results:
A total of 85 patients with acute anterior wall MI were studied, 58(68.2%) were males and 27(31.8%) were females. The mean age for males was 58.72+12.13 years and for females it was 59.69±8.17 years. On echocardiography 29 patients had LVT (34.1%). Mean age of patients with LVT was 61.14±+10.74 and those without LVT 57.93?11.05 years. Among the 65 ST-elevation MI (STEMI) patients 28 (43.1%) got LV Thrombus and in 20 non-ST-elevation MI (NSTEMI) patients only 1(5%) had LVT. In 52 patients who were diagnosed within 12 hours of onset of chest pain 8 (15.4%) developed LVT. While in 33 patients whose MI was diagnosed after 12 hours of onset of chest pain 21 (63.6%) were complicated with LV Thrombus.
Conclusion:
The incidence of LVT after acute anterior MI in our population is quite significant. Male patients, older than 50 years of age, suffering from STEMI may be at increased risk of post infarct LVT. Early hospitalization seems to lower the risk of LVT.
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