Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.7K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.7K
Epilepsy ll: Types01:22

Epilepsy ll: Types

1
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
1
Seizures l: Introduction01:20

Seizures l: Introduction

2
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
2
Seizures: Classification01:13

Seizures: Classification

2.4K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
2.4K
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

1.3K
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
1.3K
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein01:20

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

1.2K
Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improvement trend for individual health guidance intervention according to Japan clinical guidelines by public health nurses for type 2 diabetes mellitus who visited for medical checkups regularly: a case-control preliminary report.

Journal of clinical biochemistry and nutritionยท2024
Same author

Prevalence of adult epilepsy in a general Japanese population: The Hisayama study.

Epilepsia openยท2019
Same author

[Recent Advances in the Medical Care and Treatment of Epilepsy: VII. New-onset Epilepsy in the Elderly].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicineยท2018
Same author

[Recent Advances in the Medical Care and Treatment of Epilepsy: VIII. Driving Regulations in the Patients with Epilepsy].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicineยท2018
Same author

Outcome of vagus nerve stimulation for drug-resistant epilepsy: the first three years of a prospective Japanese registry.

Epileptic disorders : international epilepsy journal with videotapeยท2017
Same author

[Participation of People with Epilepsy in Sports].

Brain and nerve = Shinkei kenkyu no shinpoยท2017

Related Experiment Video

Updated: Apr 17, 2026

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

10.2K

[Migraine and epilepsy].

Sadatoshi Tsuji1

  • 1Department of Medical Technology and Sciences, School of Health Sciences at Fukuoka, International University of Health and Welfare.

Rinsho Shinkeigaku = Clinical Neurology
|February 13, 2015
PubMed
Summary

Migraine and epilepsy share clinical features and pathophysiological mechanisms, with a complex temporal association. Research explores their bidirectional relationship and potential shared genetic basis.

Area of Science:

  • Neurology
  • Neuroscience

Background:

  • Migraine and epilepsy are common episodic neurological disorders with known comorbidity.
  • The temporal relationship between migraine and epilepsy is complex and debated, with various recognized associations between headache and epileptic seizures.

Observation:

  • The International Classification of Headache Disorders, 3rd edition (ICHD-3) defines specific entities like migraine aura-triggered seizures (migralepsy) and post-ictal headaches.
  • Previous reports of migralepsy often described occipital seizures mimicking migraine with aura, though the term is now debated.
  • Migraine and epilepsy share underlying pathophysiological mechanisms, including neurotransmitter and ion channel dysfunctions.

Findings:

  • A complex and bidirectional association exists between migraine and epilepsy.

More Related Videos

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.9K
Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.9K

Related Experiment Videos

Last Updated: Apr 17, 2026

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

10.2K
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.9K
Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.9K
  • There is a hypothesis suggesting a shared genetic susceptibility to both migraine and epilepsy.
  • Familial hemiplegic migraine provides strong support for a shared genetic basis.

    • Implications:

    • Understanding the shared mechanisms and genetic links can lead to better diagnostic and therapeutic strategies for both conditions.
    • Further research into the bidirectional relationship may clarify the causality and influence between migraine and epilepsy.
    • Clarifying the controversial term 'migralepsy' and its underlying mechanisms is crucial for accurate diagnosis and treatment.