Related Experiment Video
Updated: Apr 17, 2026

Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
Published on: August 4, 2018
[Drug development for overcoming dementia in Japan]
1National center of Neurology and Psychiatry.
Abstract:
Dementia is an acquired syndrome characterized by a loss of memory and a decline in executive functions, leading to impairment in the quality of life of patients. Therefore, this syndrome has a significant economic burden on the health care system, on patients, on family and friends who provide unpaid care, and on the wider economy and society. Alzheimer's disease (AD) is the most common cause of dementia, and continued research and new therapeutic development into AD has been expected all over the world. We discuss the way to solve a variety of challenges in developing disease-modifying drugs for AD from a viewpoint of regulatory science.
Related Concept Videos
Alzheimer's Disease: Treatment
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Alzheimer Disease l: Introduction
Dementia
The progression of dementia is generally gradual....
Alzheimer Disease ll: Pathophysiology
Dementia l: Introduction

