Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modulation of Macrophages Differentiation by Nanoscale-Engineered Geometric and Chemical Features.

ACS applied bio materials·2022
Same author

Antibacterial properties of nitric oxide-releasing porous silicon nanoparticles.

Journal of materials chemistry. B·2020
Same author

Organ-specific isoform selection of fatty acid-binding proteins in tissue-resident lymphocytes.

Science immunology·2020
Same author

Local heroes or villains: tissue-resident memory T cells in human health and disease.

Cellular & molecular immunology·2020
Same author

NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice.

Science advances·2019
Same author

Correction: Rapid fabrication of functionalised poly(dimethylsiloxane) microwells for cell aggregate formation.

Biomaterials science·2017

Related Experiment Video

Updated: Apr 17, 2026

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
08:02

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

11.3K

Plasma polymerised polyoxazoline thin films for biomedical applications.

M N Ramiasa1, A A Cavallaro, A Mierczynska

  • 1Mawson Institute, UniSA, Mawson Lakes, SA 5095, Australia. krasimir.vasilev@unisa.edu.au.

Chemical Communications (Cambridge, England)
|February 13, 2015
PubMed
Summary

Plasma polymerized poly(2-oxazoline)s offer a revolutionary, solvent-free method for creating biocompatible coatings. These advanced biomaterials control cell adhesion and reduce biofilm formation, surpassing traditional techniques.

More Related Videos

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.9K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.8K

Related Experiment Videos

Last Updated: Apr 17, 2026

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
08:02

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

11.3K
Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.9K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.8K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Surface Engineering

Background:

  • Poly(2-oxazoline)s (POx) are promising biomaterials with properties rivaling established alternatives.
  • Current synthesis methods for POx coatings are often complex and time-consuming (wet synthesis).
  • There is a need for efficient, versatile methods to produce POx coatings for biomedical applications.

Purpose of the Study:

  • To develop a novel, efficient method for creating poly(2-oxazoline) coatings.
  • To demonstrate the substrate-independent and solvent-free nature of the new coating process.
  • To evaluate the ability of these nanoscale coatings to control protein and cell adhesion and reduce biofilm formation.

Main Methods:

  • Plasma polymerization was employed to deposit poly(2-oxazoline) coatings.
  • The synthesis was performed under solvent-free conditions.
  • The resulting nanoscale coatings were characterized for their ability to influence protein and cell interactions and inhibit biofilm.

Main Results:

  • Successfully developed solvent-free, substrate-independent plasma polymerized poly(2-oxazoline) coatings.
  • Demonstrated control over protein and cell adhesion on the nanoscale coatings.
  • Significantly reduced bacterial biofilm build-up compared to controls.

Conclusions:

  • Plasma polymerized poly(2-oxazoline)s represent a significant advancement in biomaterial coatings.
  • This novel method offers a versatile and efficient alternative to traditional wet synthesis.
  • The developed coatings show great potential for applications requiring control over biofouling and cell interactions.