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Ileocecal ulcers accompanied by relapsing polychondritis: a case report
Yoko Kawakami1, Katsuya Endo1, Tomonori Ishii2
1Division of Gastroenterology, Department of Internal Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba-ku, Sendai, 980-8574 Japan.
Springerplus
|February 13, 2015
Summary
A rare case of MAGIC syndrome presented with ileocecal ulcers and relapsing polychondritis (RP) but lacked typical Behçet
Area of Science:
- Rheumatology
- Gastroenterology
- Internal Medicine
Background:
- Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is a rare overlap of Behçet's disease (BD) and relapsing polychondritis (RP).
- Gastrointestinal manifestations in MAGIC syndrome are uncommon and poorly understood.
Purpose of the Study:
- To describe a unique case of MAGIC syndrome presenting with ileocecal ulcers.
- To highlight the diagnostic and therapeutic challenges in such rare cases.
Main Methods:
- A 30-year-old female with a history of RP presented with abdominal pain and bloody stools.
- Colonoscopy revealed ileocecal ulcers resembling intestinal BD.
- Ileocecal resection was performed, followed by infliximab treatment for recurrent symptoms.
Main Results:
- The patient exhibited ileocecal ulcers without fulfilling major diagnostic criteria for BD.
- The gastrointestinal lesions showed features similar to intestinal BD.
- Infliximab treatment led to improvement of both RP and gastrointestinal symptoms.
Conclusions:
- This case represents a potential rare subtype of MAGIC syndrome.
- Ileocecal ulcers can occur in MAGIC syndrome even without overt BD symptoms.
- Infliximab may be effective in managing gastrointestinal manifestations of this condition.
