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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
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Brown fat FDG uptake abolished by radiotherapy
Shivany Gnaneswaran1, Brendan Tandy, Michael J Fulham
1From the *Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia; and †Sydney Medical School, University of Sydney, Camperdown, New South Wales, Australia.
Clinical Nuclear Medicine
|February 13, 2015
Summary
This study highlights how brown fat FDG uptake on PET/CT scans can be affected by radiation therapy in non-small cell lung cancer patients. Understanding these patterns is crucial for accurate cancer progression assessment.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiology
Background:
- Non-small cell lung cancer (NSCLC) recurrence necessitates accurate staging and progression assessment.
- Fluorine-18 fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (F-FDG PET/CT) is a key imaging modality in NSCLC management.
- Previous radiation therapy can influence F-FDG uptake patterns in brown adipose tissue (BAT).
![Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62460.jpg&w=3840&q=50)