[Endoscopic mucosal resection and submucosal dissection of the gut neuroendocrine tumors]

Klinichna Khirurhiia
|February 14, 2015
PubMed

Insights

Endoscopic mucosal resection (EMR) and submucosal dissection (SD) are effective treatments for gut neuroendocrine tumors (NET). These minimally invasive endoscopic techniques successfully removed NETs in five patients across various gastrointestinal locations.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Endoscopic Surgery

Context:

  • Neuroendocrine tumors (NETs) are a diverse group of neoplasms originating from neuroendocrine cells.
  • Minimally invasive endoscopic techniques are increasingly utilized for gastrointestinal tumor resection.
  • Evaluating the efficacy of endoscopic resection for specific NET locations is crucial for treatment planning.

Purpose:

  • To assess the efficacy of endoscopic mucosal resection (EMR) and submucosal dissection (SD) for treating gastrointestinal neuroendocrine tumors (NETs).
  • To evaluate the outcomes of miniinvasive endoscopic excision of NETs in a clinical setting.

Summary:

  • A study reviewed five patients treated for NETs between 2009 and 2013.
  • NETs were located in the stomach (2 patients), duodenal ampulla (1), terminal ileum (1), and rectum (1).
  • Gastric tumors were resected using EMR with a distal cap; duodenal and rectal tumors via SD; and ileal tumors via EMR, demonstrating successful endoscopic removal.

Impact:

  • Minimally invasive endoscopic excision, including EMR and SD, is confirmed as an effective treatment modality for gastrointestinal NETs.
  • These endoscopic approaches offer a viable alternative to traditional surgery for selected NETs, potentially reducing patient morbidity.
  • The findings support the expanded use of EMR and SD in managing NETs at various gastrointestinal sites.

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