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Sentinel lymph node biopsy for head and neck Merkel cell carcinoma: a preliminary study
A-S Ricard1, Q Sessiecq1, F Siberchicot1
1Service de Chirurgie Maxillo-Faciale, Centre François-Xavier-Michelet, Hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
Introduction:
A retrospective preliminary study assessed the feasibility of sentinel lymph node biopsy (SLNB) in the management of Merkel cell carcinoma (MCC) of the head and neck.
Patients And Methods:
Twelve patients with stage I or II head and neck MCC underwent SLNB over a 4-year period.
Results:
Only 1 of the 12 patients had a positive SLNB. The sentinel node was not identified in 3 patients. Two of the 8 patients with negative SLNB showed regional lymph node recurrence within 2years. One patient died during follow-up.
Conclusion:
Merkel cell carcinoma is an uncommon but highly aggressive pathology; management protocols have been based on small series. The role of SLNB in the management of MCC remains to be defined.
