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Transfusion-Related Acute Lung Injury After IVIG for Myasthenic Crisis
Dereddi Raja S Reddy1, Pramod K Guru, Melissa M Blessing
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW RO_OL_2_115CCS, Rochester, MN, 55905, USA, reddy.dereddiraja@mayo.edu.
Background:
A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin.
Methods:
Case report.
Results:
Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode.
Conclusions:
IVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.
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