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Effect of aging on saccular function
Mehri Maleki1, Zahra Jafari2, Homa Zarrinkoob3
11. Audiologist, MS, Department of Audiology, School of Rehabilitation Sciences, Shahid Besheshti University of Medical Sciences, Iran. mehri.maleki.a@gmail.com.
Medical Journal of the Islamic Republic of Iran
|February 14, 2015
Summary
Aging significantly impacts saccular function, detectable through cervical vestibular evoked myogenic potentials (cVEMP). This test effectively screens for early vestibular dysfunction in older adults.
Area of Science:
- Neuroscience
- Otolaryngology
- Gerontology
Background:
- Aging is associated with balance loss, leading to physical and psychological issues.
- Otolith organs play a crucial role in maintaining postural stability.
- Saccular function changes with age, impacting balance.
Purpose of the Study:
- To investigate the effect of aging on saccular function.
- To evaluate the utility of cervical vestibular evoked myogenic potentials (cVEMP) in assessing age-related saccular changes.
Main Methods:
- Comparison of cVEMP responses between young adults (n=31) and old adults (n=31).
- Participants had normal hearing and no history of balance problems.
- cVEMP recorded using 500 Hz tone burst stimuli at 95 dB nHL via air-conduction.
Main Results:
- Significant differences observed in cVEMP response threshold, P1 wave latency, P1/N1 amplitude, and amplitude asymmetry ratio between age groups.
- No significant differences in N1 wave latency or between left/right ears.
Conclusions:
- cVEMP abnormalities are evident in healthy older adults, indicating test sensitivity for early vestibular dysfunction.
- cVEMP is a practical, objective screening tool for detecting vestibular disorders.
- Early detection of vestibular dysfunction can help mitigate age-related balance issues.
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