Prevalence of microcytosis in neonates: a cross-sectional study in Tehran
Nasrin Khalesi1, Nastaran Khosravi2, Mohammad Reza Rezaee3
11. MD, Assistant Professor, Neonatologist, Pediatrics Department, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. nasrinkhalessi6@gmail.com.
Background:
Identification of α thalassemia (α thal) a common cause of microcytosis during neonatal periods is an important step prevent unnecessary interventions. Thus, low the mean corpuscular volume (MCV) and the mean corpuscular hemoglobin (MCH) may consider as α-thalassemia key detection points. The present study aimed to determine the prevalence of microcytosis among neonates who born in Tehran, Iran.
Methods:
Cord blood samples were collected from 1001 newborns after birth in labor room and their red blood cell parameters were investigated.
Results:
MCV was 114.2 fl (95% CI: 113.5-114.9) and twenty three neonates (2.3%) had MCV less than 94 fL that classified as microcytosis and 4 (0.40%) had both low MCH and MCV.
Conclusion:
Low MCV especially in normal Hb newborns may hints for α thal detection.
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