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Doppler Optical Coherence Tomography of Retinal Circulation
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One specific velocity color mapping using optical coherence tomography.

Sergey G Proskurin, Anton Yu Potlov, Sergej V Frolov

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    This study introduces a novel optical coherence tomography method for mapping flow velocities. The technique effectively visualizes complex fluid dynamics, distinguishing stationary and moving components for detailed analysis.

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    Area of Science:

    • Biomedical Optics
    • Fluid Dynamics
    • Medical Imaging

    Background:

    • Accurate velocity mapping in biological flows is crucial for diagnosing various conditions.
    • Traditional methods face limitations in resolving complex flow patterns and simultaneous structural information.

    Purpose of the Study:

    • To develop and validate a novel optical coherence tomography (OCT) technique for depth-resolved velocity mapping.
    • To demonstrate the capability of the system in visualizing sign-variable flows with complex geometries.

    Main Methods:

    • Utilized depth-resolved coherence gating and Doppler shift detection for velocity mapping.
    • Employed a bidirectional rapid scanning optical delay in the reference arm of the OCT system.
    • Used a tilted capillary as a hydrodynamic phantom to model complex, sign-variable flow.

    Main Results:

    • Successfully obtained simultaneous structural and specific velocity images.
    • Decomposed standard structural images into stationary, positive, and negative velocity components.
    • Generated equivelocity maps for positive and negative flow distributions, visualized as a complexation of the three components.

    Conclusions:

    • The developed OCT method enables precise, depth-resolved velocity mapping in complex flow scenarios.
    • This technique provides a comprehensive visualization of flow dynamics, integrating structural and velocity information.
    • The findings offer potential for enhanced diagnostic capabilities in fluid-dependent medical applications.