Related Experiment Video
Updated: Apr 17, 2026
10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
11.8K
Mutlifocal osseous posttransplantation lymphoproliferative disorder: case report
Ryan Lo1, Zachary Michalicek, Martin Lazarus
1Department of Radiology, University of Chicago, 5841 South Maryland Avenue, MC 2026, Chicago, IL, 60637, USA, dr.ryan.lo@gmail.com.
Skeletal Radiology
|February 15, 2015
Summary
Posttransplant lymphoproliferative disorder (PTLD) can affect bones, though it is rare. This case highlights PTLD misdiagnosed as gout, emphasizing the need for better imaging characterization of osseous PTLD.
Area of Science:
- Transplant medicine
- Oncology
- Radiology
Background:
- Posttransplant lymphoproliferative disorder (PTLD) is a serious complication following organ transplantation.
- Musculoskeletal involvement, specifically osseous PTLD, is an exceptionally rare manifestation.
Observation:
- A heart transplant recipient presented with recurrent bone lesions over several years.
- The condition was initially misdiagnosed as gout, delaying appropriate diagnosis and treatment.
Findings:
- This case underscores the diagnostic challenges of osseous PTLD.
- Characterizing imaging findings across multiple modalities is crucial for accurate identification.
Implications:
- Improved understanding of osseous PTLD imaging can aid early diagnosis in transplant patients.
- This can lead to timely intervention and potentially better patient outcomes.
- Highlights the importance of considering rare diagnoses in transplant recipients with persistent symptoms.
