Iatrogenic pneumothorax in mechanically ventilated children: Incidence, risk factors and other outcomes
Paulo Sérgio Lucas da Silva1, Vânia Euzébio de Aguiar1, Marcelo Cunio Machado Fonseca2
1Department of Pediatrics, Pediatric Intensive Care Unit, Hospital do Servidor Público Municipal, Rua Castro Alves, 60, São Paulo 01532-900, Brazil.
Insights
Iatrogenic pneumothoraces (IPs) occurred in 3% of pediatric intensive care unit patients on mechanical ventilation. Thoracic invasive procedures significantly predicted IPs, which were linked to higher mortality rates.
Area of Science:
- Pediatric Critical Care Medicine
- Pulmonary Medicine
- Patient Safety
Background:
- Iatrogenic pneumothoraces (IPs) are a potential complication in critically ill children.
- Mechanical ventilation (MV) and invasive procedures increase the risk of IPs.
Purpose of the Study:
- To determine the prevalence, risk factors, and outcomes of IPs in a pediatric intensive care unit (PICU).
Main Methods:
- A 5-year prospective cohort study included 645 pediatric intensive care unit patients receiving mechanical ventilation.
- Twenty cases of iatrogenic pneumothorax were compared to eighty control patients.
Main Results:
- The overall prevalence of iatrogenic pneumothorax was 3%.
- Thoracic invasive procedures were a significant predictor (OR 11) of iatrogenic pneumothorax.
- Patients with iatrogenic pneumothorax had a significantly higher mortality rate.
Conclusions:
- Thoracic invasive procedures are strongly associated with iatrogenic pneumothoraces in mechanically ventilated children.
- Quality improvement programs may help prevent iatrogenic pneumothoraces.
Objectives:
Determine prevalence, risk factors and outcomes of iatrogenic pneumothoraces (IPs) in a pediatric intensive care unit (PICU).
Methods:
Patients with IP (cases) and patients without IP (controls) were retrieved from a 5-year prospective cohort of 645 PICU patients who received mechanical ventilation (MV).
Results:
Twenty cases and eighty controls were assessed. The overall prevalence of IP was 3%. Eleven IPs were procedure-related IP and 9 MV related. Performance of thoracic invasive procedures (odds ratio 11) was the significant IP predictor in the logistic regression analysis. IP incidence was higher within 12 hours. There were no differences between the groups concerning duration of MV, length of PICU and hospital stays. IP patients had a significantly higher mortality rate (p = 0.005).
Conclusions:
Performance of thoracic invasive procedures was strongly associated with IPs events in mechanically ventilated children. Many of these events may potentially be preventable with the implementation of quality improvement programs.
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