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Updated: Apr 17, 2026

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
New options for vascularized bone reconstruction in the upper extremity.
Matthew T Houdek1, Eric R Wagner1, Cody C Wyles2
1Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Vascularized bone grafting effectively treats upper extremity bone defects and non-unions. Techniques like the vascularized fibula, scapula, and medial femoral condyle (MFC) flap offer solutions for various bone pathologies.
Area of Science:
- Orthopedic Surgery
- Regenerative Medicine
- Musculoskeletal Research
Background:
- Vascularized bone grafting, established since the 1970s, is crucial for bony defects and non-unions.
- While common in lower extremities, novel techniques are emerging for complex upper extremity conditions.
Purpose of the Study:
- To review diverse vascularized bone grafting techniques for upper extremity pathologies.
- To highlight current standards and emerging options for bone reconstruction in the arm and hand.
Main Methods:
- Review of established and novel vascularized bone grafting techniques.
- Analysis of graft suitability for different upper extremity bone defects and non-unions.
Main Results:
- The vascularized fibula is the gold standard for large humerus/forearm defects and carpal reconstruction.
- Other options include vascularized scapula grafts, Capanna technique, MFC free flap, and rib transfers.
- Specific techniques are viable for carpal non-unions and epiphyseal transfer offers growth potential in pediatric cases.
Conclusions:
- A range of vascularized bone grafts effectively address upper extremity bone defects and non-unions.
- Technique selection depends on defect size, location, and patient skeletal maturity.
- Vascularized bone grafting continues to advance reconstructive possibilities in the upper extremity.
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Published on: August 13, 2017
10:36Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
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