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Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Quanlong Lu1, Christine Insinna1, Carolyn Ott2

  • 1NCI-Frederick National Laboratory, Laboratory of Cellular and Developmental Signaling, Frederick, MD 21702, USA.

Nature Cell Biology
|February 17, 2015
PubMed
Summary

Membrane proteins EHD1 and EHD3 reorganize the mother centriole (M-centriole) and vesicles, initiating ciliary membrane assembly. This process is crucial for ciliogenesis before axoneme growth.

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