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Synthesis of some 2-(3,4-dimethoxy-phenyl)-1,3-propanediamines as potential dopaminergic agents
R M Shafik1, E A Ibrahim, E M el-Khawass
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria.
Die Pharmazie
|February 1, 1989
Abstract:
The bilateral diamino analogs namely N,N'-dialkyl-N,N'-diaralkyl- and N,N,N',N'-tetraalkyl-2-(3,4-dimethoxyphenyl)-1,3-propanediamine s were synthesized. The biochemical determination of the brain levels of dopamine and norepinephrine as well as of brain monoamine oxidase (MAO) activity was performed.