Related Experiment Video
Updated: Apr 17, 2026
Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
Published on: June 17, 2016
Micropatterned, clickable culture substrates enable in situ spatiotemporal control of human PSC-derived neural tissue
G T Knight1, J Sha, R S Ashton
1Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA. rashton2@wisc.edu.
Abstract:
We describe a modular culture platform that enables spatiotemporal control of the morphology of 2D neural tissues derived from human pluripotent stem cells (hPSCs) by simply adding clickable peptides to the media. It should be widely applicable for elucidating how spatiotemporal changes in morphology and substrate biochemistry regulate tissue morphogenesis.
More Related Videos
10:04Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics
Published on: September 28, 2019
08:48Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells
Published on: August 16, 2018