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Schizencephaly-diagnostics and clinical dilemmas
Agata Halabuda1, Lukasz Klasa, Stanislaw Kwiatkowski
1Department of Radiology, Polish-American Institute of Pediatrics/Jagiellonian University, 265 Wielicka St., 30-663, Kraków, Poland, agatahalabuda@gazeta.pl.
Schizencephaly, a brain cleft disorder, presents diagnostic challenges. Imaging can help differentiate it from other fluid spaces, guiding treatment decisions based on clinical presentation, especially intracranial hypertension.
Area of Science:
- Neuroscience
- Developmental Biology
- Medical Imaging
Background:
- Schizencephaly is a rare congenital brain disorder involving a cleft from the pia mater to the ventricles.
- The cleft is lined with abnormal gray matter, with heterogeneous causes including genetic mutations and environmental factors.
- Accurate diagnosis is crucial for appropriate management of this cerebral cortical development defect.
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