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Updated: Apr 17, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Sinonasal angiosarcoma
F Es-Sbissi1, S Nitassi1, M Boulaadas1
1Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
Introduction:
Angiosarcoma is a malignant tumour arising from endothelial cells that accounts for 1% of all sarcomas. The sinonasal site of angiosarcoma is exceptional.
Case Report:
The authors report a case of sinonasal angiosarcoma in a 53-year-old man. Despite wide resection by open surgery and postoperative chemoradiotherapy, several tumour recurrences were observed, requiring multiple operations.
Discussion:
Only histological examination with immunohistochemistry is able to confirm the diagnosis (factor VIII, CD34 and CD31 antigens). Standard treatment consists of surgery with wide resection followed by radiotherapy. The authors discuss the treatment modalities and prognosis of this tumour.
