Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Minimum mortality temperature by cause of death and age group: A multi-country observational study (1990-2019).

Environmental research·2026

Same author

Long-term exposure to elemental carbon and disease incidence: a systematic review and meta-analysis.

Environmental health : a global access science source·2025

Same author

Laparoscopic Heller myotomy versus peroral endoscopic myotomy in children with esophageal achalasia: a systematic review and meta-analysis.

Annals of gastroenterology·2024

Same author

Temporal change in minimum mortality temperature under changing climate: A multicountry multicommunity observational study spanning 1986-2015.

Environmental epidemiology (Philadelphia, Pa.)·2024

Same author

Total and H-specific growth/differentiation factor 15 levels are unaffected by liraglutide or naltrexone/bupropion administration.

Diabetes, obesity & metabolism·2024

Same author

Comparison for the effects of different components of temperature variability on mortality: A multi-country time-series study.

Environment international·2024

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

Comparative changes in tissue oxygenation between laparoscopic and open cholecystectomy.

George D Bablekos¹, Stylianos A Michaelides², Antonis Analitis³

¹Department of Experimental Physiology, Medical School, Democritous University of Thrace, 68100 Dragana, Alexandroupolis, Greece ; Technological Educational Institute (T.E.I.) of Athens, Agiou Spyridonos 28 Street, 12243 Egaleo, Athens, Greece.

Journal of Clinical Medicine Research

|February 21, 2015

Summary

This summary is machine-generated.

Laparoscopic cholecystectomy (LC) may pose a lower risk for impaired tissue oxygenation compared to open cholecystectomy (OC). Postoperative gas exchange, including alveolar-arterial difference in PO2, shows better outcomes with LC.

Keywords:

Arterial oxygenation Cholecystectomy Laparoscopic Open

More Related Videos

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Published on: June 16, 2023

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Published on: May 2, 2025

Related Experiment Videos

Last Updated: Apr 17, 2026

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Published on: June 16, 2023

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Published on: May 2, 2025

Area of Science:

Surgical outcomes
Respiratory physiology
Gas exchange

Background:

Previous research has explored the respiratory effects of laparoscopic cholecystectomy (LC) versus open cholecystectomy (OC).
This study specifically compares arterial blood gas parameters between LC and OC to evaluate their impact on gas exchange.

Purpose of the Study:

To compare changes in arterial blood gases and related parameters between LC and OC.
To assess the comparative influence of LC and OC on postoperative gas exchange.

Main Methods:

A study of 28 patients (18 LC, 10 OC) under identical anesthesia.
Measurements of alveolar-arterial difference in PO2 ((A-a)DO2) and oxygen content (Oct in vol%) were taken before surgery (BS), on postoperative day 2 (AS2), and day 8 (AS8).

Main Results:

On AS2, OC showed a greater increase in (A-a)DO2 compared to LC.
Oxygen content (Oct) decreased from BS to AS2 in both groups, with a further reduction in OC between AS2 and AS8.
On AS2, the decrease in oxygen saturation (SaO2%) was more pronounced in the OC group.

Conclusions:

The increased (A-a)DO2, reduced Oct, and decreased SaO2% observed in the OC group on AS2 suggest potential for impaired tissue oxygenation.
Laparoscopic cholecystectomy (LC) may be associated with a lower risk of impaired tissue oxygenation compared to open cholecystectomy (OC).