Related Experiment Video
Updated: Apr 17, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Common childhood viral infections
Sherman J Alter1, Jeffrey S Bennett2, Katylin Koranyi3
1Wright State University, Boonshoft School of Medicine, Dayton, OH; Division of Infectious Diseases, Dayton Children's Hospital, Dayton, OH.
Insights
Viral infections are common in children, with varied presentations and outcomes. While many are self-limiting, prevention through vaccination and treatment with antivirals are key for managing these common childhood illnesses.
Area of Science:
- Pediatrics
- Virology
- Infectious Diseases
Background:
- Viral infections are ubiquitous in children and adolescents, presenting diverse clinical manifestations.
- Maternal infections can impact fetuses, while other viruses follow age-specific patterns.
- Vaccination has eradicated many past viral threats, but vigilance is needed against resurgent diseases like measles and mumps.
Purpose of the Study:
- To review the epidemiology, clinical presentation, diagnosis, treatment, and prevention of common viral infections in pediatric patients.
- To highlight the importance of vaccination and antiviral therapies in managing childhood viral illnesses.
- To provide clinicians with essential information for identifying and managing viral infections in children and adolescents.
Main Methods:
- Literature review of common viral infections in pediatric populations.
- Analysis of epidemiological data, clinical presentations, diagnostic approaches, and treatment strategies.
- Synthesis of information on vaccine-preventable diseases and emerging antiviral treatments.
Main Results:
- Viral infections exhibit a wide range of presentations influenced by pathogen, age, and immune status.
- Vaccination has significantly reduced the incidence of many viral diseases, though outbreaks still occur.
- Antiviral medications offer effective treatment for an increasing number of viral infections, including herpes simplex virus, influenza, varicella zoster virus, and cytomegalovirus.
Conclusions:
- Most viral infections in children are self-limited and managed symptomatically, leading to full recovery.
- Continued vaccination efforts are crucial for preventing the re-emergence of vaccine-preventable viral diseases.
- Advances in antiviral therapies improve management options for specific viral infections in pediatric care.
Abstract:
Infections caused by viruses are universal during childhood and adolescence. Clinicians will regularly care for children and adolescents who present with infections caused by a wide number of viral pathogens. These infections have varied presentations. Many infections may have clinical presentations that are specific to the infecting virus but present differently, based on the age and immunocompetence of the patient. Some children are directly impacted early in their lives when maternal disease results in an in utero infection (cytomegalovirus, rubella virus, or parvovirus B19). Other viruses may infect children in a predictable pattern as they grow older (rhinovirus or influenza virus). Fortunately, many viral infections frequently encountered in the past are no longer extant due to widespread immunization efforts. Recognition of these vaccine-preventable infections is important because outbreaks of some of these diseases (mumps or measles) continue to occur in the United States. Vigilance in vaccine programs against these viral agents can prevent their re-emergence. In addition, an increasing number of viral infections (herpes simplex virus, influenza virus, varicella zoster virus, or cytomegalovirus) can now be successfully treated with antiviral medications. Most viral infections in children result in self-limited illness and are treated symptomatically and infected children experience full recovery. This review will address the epidemiology, clinical presentation, diagnosis, treatment, and prevention of viral infections commonly encountered by the clinician.
More Related Videos
05:51Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
08:44Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Related Concept Videos
Viral Meningitis
Cytomegalovirus Disease
Human Virome
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Viral Recombination
Immunodeficiency Diseases
There are three main causes of immunodeficiency...