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Updated: Apr 17, 2026
09:01
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
8.5K
Common childhood viral infections.
Sherman J Alter1, Jeffrey S Bennett2, Katylin Koranyi3
1Wright State University, Boonshoft School of Medicine, Dayton, OH; Division of Infectious Diseases, Dayton Children's Hospital, Dayton, OH.
Current Problems in Pediatric and Adolescent Health Care
|February 24, 2015
Summary
Viral infections are common in children, with varied presentations and outcomes. While many are self-limiting, prevention through vaccination and treatment with antivirals are key for managing these common childhood illnesses.
Area of Science:
- Pediatrics
- Virology
- Infectious Diseases
Background:
- Viral infections are ubiquitous in children and adolescents, presenting diverse clinical manifestations.
- Maternal infections can impact fetuses, while other viruses follow age-specific patterns.
- Vaccination has eradicated many past viral threats, but vigilance is needed against resurgent diseases like measles and mumps.
Purpose of the Study:
- To review the epidemiology, clinical presentation, diagnosis, treatment, and prevention of common viral infections in pediatric patients.
- To highlight the importance of vaccination and antiviral therapies in managing childhood viral illnesses.
- To provide clinicians with essential information for identifying and managing viral infections in children and adolescents.
Main Methods:
- Literature review of common viral infections in pediatric populations.
- Analysis of epidemiological data, clinical presentations, diagnostic approaches, and treatment strategies.
- Synthesis of information on vaccine-preventable diseases and emerging antiviral treatments.
Main Results:
- Viral infections exhibit a wide range of presentations influenced by pathogen, age, and immune status.
- Vaccination has significantly reduced the incidence of many viral diseases, though outbreaks still occur.
- Antiviral medications offer effective treatment for an increasing number of viral infections, including herpes simplex virus, influenza, varicella zoster virus, and cytomegalovirus.
Conclusions:
- Most viral infections in children are self-limited and managed symptomatically, leading to full recovery.
- Continued vaccination efforts are crucial for preventing the re-emergence of vaccine-preventable viral diseases.
- Advances in antiviral therapies improve management options for specific viral infections in pediatric care.
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