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Cardiac Resynchronization Therapy in Infant with Dilated Cardiomyopathy during Extracorporeal Membrane Oxygenator

Ji Hyun Bang1, You Na Oh1, Jae-Kon Ko2

  • 1Division of Pediatric Cardiac Surgery, Asan Medical Center, University of Ulsan College of Medicine.

The Korean Journal of Thoracic and Cardiovascular Surgery
|February 24, 2015
PubMed

Insights

Cardiac resynchronization therapy (CRT) may improve outcomes for infants with dilated cardiomyopathy (DCMP). This study reports successful CRT in an infant with DCMP during extracorporeal membrane oxygenation, showing promising results.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Research
  • Biomedical Engineering

Background:

  • Dilated cardiomyopathy (DCMP) in infants presents challenges, with heart transplantation limited by donor availability.
  • Cardiac resynchronization therapy (CRT) is effective for adults with DCMP and cardiac dyssynchrony.
  • Evidence for CRT's effectiveness in infants with DCMP is limited.

Observation:

  • This case report details the application of CRT in an infant diagnosed with DCMP.
  • The infant required support via extracorporeal membrane oxygenation during the procedure.
  • A follow-up period of 5 months was conducted post-intervention.

Findings:

  • The study observed improvements in hemodynamic parameters and cardiac performance following CRT.
  • The infant tolerated the CRT procedure well while on extracorporeal membrane oxygenation.
  • Sustained benefits were noted during the 5-month follow-up period.

Implications:

  • This case suggests CRT may be a viable therapeutic option for infants with DCMP, particularly when facing donor limitations.
  • Further research is warranted to establish the long-term efficacy and safety of CRT in pediatric DCMP patients.
  • CRT could potentially offer an alternative to heart transplantation in select pediatric populations.

Keywords:
Cardiac resynchronization therapyCardiomyopathyExtracorporeal membrane oxyenation

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