Related Experiment Video
Updated: Apr 17, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
A step forward in elucidating the mystery of OCD
Sina Kohl1, Lena Ebbert1, Alexander Sartorius2
1Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.
Abstract:
Obsessive-compulsive disorder represents one of the most disabling psychiatric disorders. The underlying pathophysiology is not fully understood. In a recent Science article, Ahmari and colleagues enlighten fundamental aspects of obsessive-compulsive disorder by means of optogenetic stimulation, thereby also elucidating the usefulness of SSRI in the treatment for OCD.
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