Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Association of miR-146a/b and miR-181a with Chronic Obstructive Pulmonary Disease.

Biochemical genetics·2026

Same author

Faecalibacterium prausnitzii and Akkermansia muciniphila: driving the multiple sclerosis-a systematic review.

Antonie van Leeuwenhoek·2026

Same author

Dose-dependent neurotoxic impact of cigarette smoking on post-stroke survival.

Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing·2026

Same author

Whole Exome Sequencing Identified a Stop-Gained Mutation in DYSF Gene Associated With Dysferlinopathy in an Iranian Family.

International journal of genomics·2025

Same author

Shortened NIHSS for Rapid Stroke Assessment in Emergency Care Settings.

The neurologist·2024

Same author

Nanocurcumin modulates Th17 cell responses in moderate and severe COPD patients.

Heliyon·2024

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Correlation between optic nerve involvement and chronic obstructive pulmonary disease.

Haleh Mikaeili¹, Mohammad Yazdchi², Shiva Solahaye Kahnamouii²

¹Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Science, Tabriz, Iran.

Clinical Ophthalmology (Auckland, N.Z.)

|February 25, 2015

Summary

This summary is machine-generated.

Chronic obstructive pulmonary disease (COPD) is linked to optic neuropathy. COPD patients showed significantly longer P100 latency, suggesting a demyelinating optic nerve issue requiring further study.

Keywords:

COPD neuropathy visual evoked potential

More Related Videos

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Apr 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

Area of Science:

Ophthalmology
Pulmonology
Neurology

Background:

Chronic obstructive pulmonary disease (COPD) presents a significant global health challenge.
Optic neuropathy is a potential complication in COPD patients.

Purpose of the Study:

To investigate the prevalence of optic neuropathy in individuals with COPD.
To assess visual evoked potentials (VEPs) in COPD patients compared to a control group.

Main Methods:

Forty COPD patients and 60 healthy controls were enrolled.
Patients were assessed using Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria.
Visual evoked potentials (VEPs) were recorded using the checkerboard method.

Main Results:

Fifty-five percent of COPD patients exhibited abnormal VEPs.
COPD patients demonstrated significantly prolonged mean P100 latency in both eyes.
P100/N140 amplitude was insignificantly higher in the COPD group.

Conclusions:

Elevated P100 latency in COPD patients indicates a demyelinating optic nerve involvement.
Further research is warranted to elucidate the relationship between COPD and optic neuropathy.